ABSTRACT
Nosocomial infections are one of the problems of past and recent centuries and are cause of the urge of cost and expenditure to patients and health systems. Therefore identification of incidence and related factors in hospital infections and prevention ways is especially important. This study was performed on 691 patients who were admitted to ICU of Shaheed Mustafa-Khomeini hospital from 1385-1386. The collection of data was done to according of questionnaire of the national nosocomial infection surveillance system [NNIS]. The clinical signs and symptoms of patients were frequently controlled. In suspected patients, necessary laboratory tests and cultures was done. Data was analyzed by SPSS version 15 software. The incidence of nosocomial infections was 10.85 percent. The most common type of infections were pneumonia 77.3%, UTI 18.3%, surgical site infection 2.7% and blood infection 1.3%, respectively. The most common microorganisms in pulmonary infections were Acinetobacter SPP, in UTI E.coli, in surgical site Staphylococcus aurous and Klebsiella and blood infection Enterococci, respectively. Incidence of pneumonia significantly is more than of other [p<0.01]. Also the correlation of ICU stay time and incidence of nosocomial infection is significant [p<0.001] .But the effect of age, gender and invasive procedures were not significant. To according of results of investigation, increasing of ICU stay time have direct relation with risk of infections. Infection control practices and sanitary methods are rational and essential part in the ICU. We suggest to use of invasive procedures limited to necessary times and use of aseptic method in treatment process